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- Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (Patients reporting increase in appetite at … Patients reporting increase in appetite at any point in the study (6-week median time): </br></br>* Significant benefit for Megestrol Acetate arm compared to Dronabinol arm (75% vs. 49%; p=0.0001)</br></br>* No differences between Megestrol Acetate + Dronabinol arm (66%) and Megestrol Acetate arm (p=0.17)m (66%) and Megestrol Acetate arm (p=0.17))