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- Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (Significantly higher prevaccinal concentra … Significantly higher prevaccinal concentrations of antibodies against polysaccharides PS1, PS5, PS6, PS9, PS14, and PS18 in both arms at both 4 and 16 week after vaccination;</br>concentrations of PS6-specific antibodies in the end of study significantly higher in the placebo arm (MW (95% CI): 2.96 (1.74–5.03), p < 0.01) (MW (95% CI): 2.96 (1.74–5.03), p < 0.01))