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List of results

Mansouri et al. (2016): The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study.)
Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study.)
Walsh et al. (2010): Use of alpha,25-dihydroxyvitamin D3 treatment to stimulate immune infiltration into head and neck squamous cell carcinoma + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study.)
Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study; ANOVA, LSD-Test, Mann-Whitney-U-Test, Wilcoxon-Test)
Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer + (The specific analysis method is not stated … The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study. Chi-square test, Student’s t-test and analysis of variance; survival curves were plotted by the Kaplan-Meier methodand statistically evaluated by the log-rank test.tistically evaluated by the log-rank test.)
Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study)
Gorgu et al. (2013): The effect of zinc sulphate in the prevention of radiation induced oral mucositis in patents with head and neck cancer + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study)
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study)
Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study)
Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms + (The specific analysis method is not stated … The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study.Chi-square-test; Student’s t test and an analysis of variance; survival curves were plottedaccording to the Kaplan-Meier method; the differences between curves were evaluated by the log-rank test.urves were evaluated by the log-rank test.)
Vinzenz et al. (1992): Die Therapie der radiogenen Mukositis mit Enzymen + (The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study; comparison of the arms with chi-square test and exact fisher test)
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis + (The specific analysis method is not stated in the study, however, according to the authors, all included patients of the subgroup analysis were evaluated at the end of the study.)
Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group + (The time to first recurrence was estimated … The time to first recurrence was estimated using the Kaplan-Meier technique and compared using a 2-sided log rank test. The recurrence rate was compared using 2-sided permutation test. Adjustment for prognostic factors was carried out by means ofretrospective stratification or, in the case of time to first recurrence, by means of the Cox proportional hazards regression model.Cox proportional hazards regression model.)
Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck + (Three interim analyses were planned: the f … Three interim analyses were planned: the first after 20 patients have completed Chemo-Radiotherapy to ensure toxicity in the selenium arm was not unacceptably high and the second and third after one third and two thirds of the patients had been followed for at least 18 monthss had been followed for at least 18 months)

Crew et al. (2012): Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor–Negative Breast Cancer + (Time-to-event continual reassessment method (TITE-CRM))

Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Tukey–Kramer procedure for multiple comparisons; planned intention-to-treat analysis, but not all participants from the baseline cycle were included in the evaluation/ more participants were evaluated than those who completed cycle 2)
Lua et al. (2015): Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer + (Two-factor (arm and time) analyses of variance)
Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy + (Two-sample t-tests: comparison of continuo … Two-sample t-tests: comparison of continuous variablesPearson’s Chi-square tests: comparison of categorical variablesMann–Whitney U-test: comparison of the grade of diarrhea and vomiting between two groupsNonparametric analysis (Friedman): comparison of the score of diarrhea and vomiting during 4 weeksre of diarrhea and vomiting during 4 weeks)
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + (Unclear when the two attritions took place, as according to the tables all were included in the analysis.)
Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients + (Univariate statistical analysis techniques, including frequency distributions, mean scores and also t tests, were also utilized for the analysis of the data.)
Stephenson et al. (2000): The Effects of Foot Reflexology on Anxiety and Pain in Patients With Breast and Lung Cancer. + (Wilcoxon and Signed-Rank tests)
Kirste et al. (2011): Boswellia serrata Acts on Cerebral Edema in Patients Irradiated for Brain Tumors. A Prospective, Randomized, Placebo-Controlled, Double-Blind Pilot Trial + (Wilcoxon rank test 2-sided testing)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Wilcoxon signed rank test and Binomial test and Mann-Whitney)
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial + (analyzed n=74)
Rostock et al. (2013): Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture + (n (Analysis) = 59, 1 drop-out in hydroelectric bath arm (no treatment received); "all randomized patients who received at least one study treatment were included in all (effectiveness or safety) analyses")
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies + (n = 2 no intervention received Wilcoxon r … n = 2 no intervention receivedWilcoxon rank-sum test was conducted for percent improvement in average pain NRS score (from baseline to end of treatment in study 1, and from eligibility pre-treatment baseline to end of treatment in study 2). Analysis of covariance (ANCOVA) was applied on the primary and the key secondary efficacy endpoints, including percent improvement, average pain/worst pain/sleep disruption scores, with corresponding baseline value as a covariate and treatment group as a factor. The time-course of these four efficacy endpoints from week 1 through week 5 was also analysed using Mixed-Effect Model Repeat Measurement (MMRM) on the ITT analysis set in both studies.For both study 1 and study 2, the primary endpoint and the key secondary endpoints were tested with their Type I error controlled by use of a hierarchical gate-keeping procedure.In each study, p-values from Wilcoxon rank-sum tests on percent improvement and ANCOVA on average pain/worst pain/sleep disruption scores were used for the hierarchical gate-keeping procedure in the sequence of the primary endpoint and the key secondary endpoints. No adjustments for covariates were made for the analyses of the other secondary endpoints in both studies with analysis of variance (ANOVA), including PGIC, SGIC or PSQ, and daily total, maintenance, and breakthrough opioid dose. Subgroup analyses for region (United States and rest of world (ROW)) were performed for the primary and the key secondary endpoints.e primary and the key secondary endpoints.)
Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (n for ITT: 243, only for tests between THC/Cannabis extract vs. Placebo n for PP: 80, tests between THC vs. Cannabis extract ITT and PP only for primary endpoint, sucessive testing labeled explorative)
Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients + (t-test)