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List of results

• Kadhim et al. (2021): Effect of Ginger Tea on Chemotherapy-Induced Nausea and Vomiting among Patients Attending the Oncology Teaching Hospital, Baghdad 2020  + (?)
• Montazeri et al. (2013): Iranian Red Crescent Medical JournalEffect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients.  + (?)
• Sharp et al. (2009): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer  + (?)
• Williams et al. (1996): Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity  + (?)

• Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy  + (Body-Mass-Index of all subjects BMI<25 … Body-Mass-Index of all subjects</br></br>BMI<25 = 60; BMI 25-29 = 78; BMI>30 = 99</br></br></br>BMI per arm</br></br>Powder arm: BMI<25 = 14 (17.72%); BMI 25-29 = 28 (35.4%); BMI>30 = 37 (46.84%)</br></br>Aloe arm: BMI <25 = 23 (28.40%); BMI 25-29 = 26 (32.10%); BMI >30 = 32 (39.51%)</br></br>Placebo arm: BMI <25 = 23 (29.87%); BMI 25-29 = 24 (31.17%); BMI >30 = 30 (38.96%)5 = 23 (29.87%); BMI 25-29 = 24 (31.17%); BMI >30 = 30 (38.96%))
• Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia  + (Cancer Cachexia)
• Cruciani et al. (2012): L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial  + (Carnitine deficiency (free carnitine < … Carnitine deficiency (free carnitine < 35 µmol/L for men or < 25 µmol/L for women or acyl/free carnitine ratio > 0.4; Baseline: intervention arm: 34% and placebo arm: 32%)</br></br>Medication (intervention/placebo arm)</br>Psychostimulants 2.1/ 3.2%</br>Analgesics 44.4/ 33.7% </br>Antidepressants 28.6/ 27.8%s 44.4/ 33.7% Antidepressants 28.6/ 27.8%)
• Cruciani et al. (2009): L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study  + (Carnitine deficiency; carnitine deficiency … Carnitine deficiency; carnitine deficiency was defined as free carnitine less than 35 µmol/L for males or less than 25 µmol/L for females (normal range 35-67 and 25-55, respectively), or an acyl-carnitine ratio of more than 0.4 (acylcarnitine ratio 0.4 total acyl-carnitine - free acyl-carnitine/free acyl-carnitine)- free acyl-carnitine/free acyl-carnitine))
• Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy  + (Chemotherapy-induced peripheral neuropathy (CIPN; grade ≥3 or grade ≥2 for at least one month))
• Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial  + (Chronic, therapy-resistant tumor pain (treated with opioids))
• Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients  + (Comorbidity with hepatitis B (n=73), hepatitis C (n=104), alcohol (n=95), and non-alcoholic steatohepatitis (n=24))
• Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente  + (Concomitant diseases in 51 patients in enz … Concomitant diseases in 51 patients in enzyme-arm (E) and control-arm (C):</br></br>Cardiopathy (temporarily decompensated): E = 5; C = 3</br></br>Inactive tuberculosis: E = 0; C = 1</br></br>Chronic duodenal ulcer: E = 1; C = 0</br></br>Renal cysts on both sides: E = 1; C = 0</br></br>Emphysema bronchitis: E = 1; C = 1</br></br>Diabetes mellitus: E = 1; C = 0</br></br>Alcoholic epilepsy: E = 0; C = 1</br></br>Previous carcinoma of another organ: E = 2; C = 2s carcinoma of another organ: E = 2; C = 2)
• Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial  + (Diabetes n=2, Alcohol consumption n=6)
• Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial  + (Diabetes, Hepatitis B, Cardiovascular disease, Thyroid disease)
• Heggie et al. (2002): A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue  + (Drainage of lymphocele: Aloe vera arm: No= 73 ; Yes,once= 13 ; Yes,>1= 21 Placebo arm: No= 64 ; Yes,once= 14 ; Yes,>1= 23)
• Rostock et al. (2013): Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture  + (Four patients (3 in hydroelectric bath arm, 1 in placebo arm) presented with additional neurological problems other than CIPN: - 2 patients: facial paresis - 1 patient: double vision - 1 patient: one had diminished strength in the right hand)
• Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial  + (Four women with type 2 diabetes completed the study)
• Hajimohammadebrahim-Ketabforoush et al. (2019): Effect of Vitamin D Supplementation on Postcraniotomy Pain After Brain Tumor Surgery: A Randomized Clinical Trial  + (Headache, hypertension, diabetes)
• Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial  + (Hypertension, Diabetes mellitus, Endocrine disease, Cardiovascular disease, Chronic kidney disease, Asthma, Orthopedic disease)
• Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial  + (Hyptertension: Aloe arm = 1 (11%); placebo arm = 1 (9%) Diabetes: Aloe arm = 0; placebo arm = 3 (27%) Dyslipidemia: Aloe arm = 1 (11%); placebo arm = 2 (18%) Pelvic surgery: Aloe arm = 4 (44%); placebo arm = 4 (36%))
• Barton et al. (2013): The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9  + (Intervention/ placebo arm: Menopausal status Premenopausal 55 (51 %)/ 56 (54 %) Postmenopausal 44 (41 %)/ 43 (42 %) Unknown 8 (8 %)/ 4 (4 %))
• Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial  + (NA)
• Jeon et al. (2016): Effect of intravenous high dose Vitamin C on postoperative pain and morphine use after laparoscopic colectomy: A randomized controlled trial  + (NI)
• Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial  + (NI)
• Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study  + (NI)
• Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer  + (NI)
• Arbabi-kalati et al. (2012): Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: A double-blind randomized clinical trial  + (NI)
• Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer  + (NI)
• Freedland et al. (2020): A Randomized Controlled Trial of a 6-month low carbohydrate intervention on disease progression in men with recurrent prostate cancer: Carbohydrate and Prostate Study 2 (CAPS2)  + (NI)
• Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study  + (NI)
• Gorgu et al. (2013): The effect of zinc sulphate in the prevention of radiation induced oral mucositis in patents with head and neck cancer  + (NI)
• Stratton et al. (2010): Oral Selenium Supplementation Has No Effect on Prostate- Specific Antigen Velocity in Men Undergoing Active Surveillance for Localized Prostate Cancer  + (NI)
• Asfour et al. (2006): Effect of high-dose sodium selenite therapy on polymorphonuclear leukocyte apoptosis in non-Hodgkin's lymphoma patients  + (NI)
• Goossens et al. (2016): Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. The SELEnium and BLAdder cancer Trial  + (NI)
• Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial  + (NI)
• Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597  + (NI)
• Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer  + (NI)
• Halyard et al. (2007): Does zinc sulfate prevent therapy-induced taste alterations in head and neck cancer patients? Results of phase III double-blind, placebo-controlled trial from the North Central Cancer Treatment Group (N01C4)  + (NI)
• Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation  + (NI)
• Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study  + (NI)
• Puri et al. (2010): Lycopene in treatment of high-grade gliomas: A pilot study  + (NI)
• Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study  + (NI)
• Braik et al. (2014): Randomized trial of vitamin B6 for preventing hand-foot syndrome from capecitabine chemotherapy  + (NI)
• Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study  + (NI)
• Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group  + (NI)
• Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial  + (NI)
• Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy  + (NI)
• Mahmoodnia et al. (2017): Ameliorative effect of lycopene effect on cisplatin-induced nephropathy in patients  + (NI)
• Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy  + (NI)