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- Dörr et al. (2007): Efficacy of Wobe-Mugos E for Reduction of Oral Mucositis after Radiotherapy + (Karnofsky index < 50%; known intoleranc … Karnofsky index < 50%; known intolerance to enzyme preparations or additives; women declining to perform a pregnancy test (HCG method) before start of the study; pregnancy or lactation; participation in another clinical study within the previous 30 days; concurrent participation in another clinical studyrrent participation in another clinical study)