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- Howells et al. (2011): Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics + (Resveratrol pharmacokinetics in blood (1) and concentration in liver tissue (2): (1) Patients’ plasma was analysed by HPLC-MS/MS for resveratrol. (2) Resveratrol was quantified in tumor and normal adjacent hepatic tissues.)