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- Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms + (The clinical response was evaluated according to WHO criteria, by repeating the radiological examinations at 2-month intervals. WHO Gradiations: Complete response Partial response Stable disease Disease control Progressive disease)