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- Vinzenz et al. (1992): Die Therapie der radiogenen Mukositis mit Enzymen + (Mean (SD) for maximum severity of mucositi … Mean (SD) for maximum severity of mucositis per arm:</br></br>Enzyme arm = 1.9 (0.56)</br></br>Control arm = 2.5 (0.59)</br></br>The mucositis was less severe in the enzyme arm. The difference is statistically significant (p=0.014).</br>Significantly more patients in the control arm were in stage III (p=0.019).e control arm were in stage III (p=0.019).)