Property:Exclusion criteria
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Lyckholm et al. (2012): A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders +
NI +
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Mahmoodnia et al. (2017): Ameliorative effect of lycopene effect on cisplatin-induced nephropathy in patients +
Allergy to lycopene; hearing loss; significant neuropathy; metastatic renal involvement +
Mansouri et al. (2016): The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial +
Suffering from any other underlying diseases; being addicted to cigars, tobacco and opioid
drugs; having a history of sensitivity to aloe vera; developing any kind of sensitivity to any material during the study; developing any acute condition during the study; and unwillingness to continue participation in the study +
Mansourian et al. (2015): The effect of "curcuma Longa" topical gel on radiation -induced oral mucositis in patients with head and neck cancer +
History of radiation therapy or chemotherapy in previous year, chemotherapy protocol in addition to radiotherapy, any allergy to condiments, especially "Turmeric root", any complications due to the use of topical gel during the study, suffering from any kind of oral disease such as active oral infection, ulcer, having any systemic disease or taking any medication +
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Women of child-bearing age and patients with a mechanical obstruction to feeding, medical treatments inducing significant changes in patient metabolism or body weight, and a history of thromboembolism. +
Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study +
Participants who had undergone prostatectomy prior to radiation therapy or who had metastatic disease at the time of radiation therapy +
Martin et al. (2002): Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial +
Palliative indications for pelvic irradiation; existence of a colostomy; known intolerance to proteolytic enzyme preparations or to contents of the study medication; participation in other clinical studies within the last 30 days +
Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer +
Previous radiotherapy in the head or neck area; functional disorders of the bone marrow, liver or kidneys; allergy to aloe +
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial +
Patients who were scheduled to receive radiotherapy during the study period, were pregnant or lactating, concurrently used other ginger-containing supplements or ingested large quantities of ginger, had a history of adverse reactions to ginger, and/or thrombocytopenia. +
Mayne et al. (2001): Randomized Trial of Supplemental beta-Carotene to Prevent Second Head and Neck Cancer +
Patients with prior upper aerodigestive tract cancers within the past 5 years, or with synchronous cancers of the esophagus or lung +
Mazdak et al. (2012): Vitamin E reduces superficial bladder cancer recurrence: A randomized controlled Trial +
Accompanying carcinoma in situ (CIS) +
Meyskens et al. (1995): Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial +
NI +
Minchom et al. (2014): An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of (...) +
Patients having an active infection, inability or unwillingness to take vitamin supplementation, had taken any vitamins within the past 28 days or receiving concomitant radical chemotherapy and radiotherapy
or antiepileptic treatment +
Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck +
Patients who underwent definitive surgery (anything beyond excisional biopsy), those with Stage IVc disease (nonregional metastatic disease), those with malignancy within the previous five years, prior radiotherapy, HIV or hepatitis C positivity, platinum hypersensitivity, inability to tolerate oral medications (in absence of feeding tube), symptomatic peripheral neuropathy, planned use of amifostine, and significant comorbidity +
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy +
Patients with co‑morbidities like diabetes, autoimmune diseases which include lupus, rheumatoid arthritis, kidney disease, liver disease and thyroid (hypothyroidism, tested pre‑enrollment by thyroid‑stimulating hormone, T4, T3) and with infections like hepatitis C and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV)/AIDS (all patients would undergo laboratory confirmation for shingles, hepatitis B, C and HIV/AIDS (at any Voluntary Confidential Counselling and Testing Centre, India) prior to inclusion in study), spinal cord injuries, peripheral vascular disorders known to be associated with peripheral neuropathy; uncontrolled diabetes or compromised cardiac function or any other major organ dysfunctions, other than cancer, which would require curtailment of full doses of paclitaxel at 175 mg/m<sup>2</sup>, 3 weekly regimens +
Montazeri et al. (2013): Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients +
Corticosteroids, digestive problems, anticoagulation, radiotherapy +
Montazeri et al. (2013): Iranian Red Crescent Medical JournalEffect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients. +
? +
Moslemi et al. (2014): Oral zinc sulphate and prevention of radiation-induced oropharyngealmucositis in patients with head and neck cancers: A double blind, randomized controlled clinical trial +
concurrent disease (diabetes mellitus, hypertension, autoimmunedisorder, chronic infllammation, cardiac disease, etc.), previously administration of cytotoxic chemotherapy or radiotherapy, patients refusal, infection of mouth and systemic infection and patients with interruption in the treatment +
Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology +
Patients with metastatic disease, diarrhea before radiotherapy, radiochemotherapy, or supplementation of selenium before radiotherapy, as well as patients who had undergone previous pelvic radiotherapy +