Property:Results during intervention
This is a property of type Text.
D
Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? +
NA +
Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? +
NA +
Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? +
NA +
Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? +
NA +
Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? +
NA +
NI +
NI +
E
Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy +
'''Change in means (SD) Baseline vs. after 90 days'''
- intervention arm: 11 (5)
- placebo arm: 2.5 (3.6)
- p=0.013 +
Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy +
'''Response rate after 90 days'''
- intervention arm: 7/9
- placebo arm: 2/8
- p=0.057
Of the six patients who did not respond to placebo, five were enrolled in an open-label retinol palmitate treatment arm. All five of these met criteria for response to therapy. +
Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy +
There was no significant difference in vomiting (frequency of grade) between green tea arm and placebo arm during 2nd-5th week (p=0.4-0.7). +
Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy +
2nd week: No significant difference in incidence of diarrhoe between the arms (p=0.4)
3rd-5th week: Significantly lower incidence of diarrhoea in green tea arm compared to placebo arm
Green tea vs. placebo:
Week 3: 14 (66.7%) vs. 9 (42.9%) p=0.04
Week 4: 16 (76.2%) vs. 7 (33.3%) p=0.002
Week 5: 17 (81.0%) vs. 8 (38.1%) p=0.002 +
Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study +
No statistically significant difference;
weight loss increased as the week of radiotherapy advanced (Friedman chi-square test 40.42 p < 0.001); statistically significant difference in body weight measured before radiotherapy and the first day after radiotherapy +
Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study +
Intervention arm: Mucositis developed in 13 of 15 patients; Grade 1 mucositis was found in 8 patients and Grade 2 in 5 patients; Grade 3 and 4 was not developed; dose of radiotherapy for the patients in whom mucositis developed i was 3600 cGy (range 2400-4400)
Placebo arm: Grade 2 mucositis was developed in 4 patients and Grade 3 in 8 patients; Grade 4 mucositis did not occur in any patient;
the median radiotherapy dose was 2000 cGy (range 1800-2800)
Statistically significant differences were found in the week mucositis developed, in the severity of mucositis, and in the RT dose at which mucositis developed in favour of the intervention arm;
mucositis began to appear in the second week at 1800 cGy; at the start of the third week and in the middle of the fourth week, it peaked and then began to lower;
after 2400 cGy, the difference in the mucositis scores between the zinc and placebo groups was statistically significant and continued to be until 6 weeks after treatment +
F
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens +
NA +
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens +
NA +
Fallahi et al. (2013): Does vitamin E protect salivary glands from I-131 radiation damage in patients with thyroid cancer? +
NA +
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies +
No differences between arms after 5 weeks (no p-value) +
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies +
Results:
* Higher change in SGIC for global impression and better change assessed by physician in 'general functional ability' of Sativex arm compared to placebo arm
* Scores in SGIC better in Sativex arm at week 3 (p = 0.041), 5 (p = 0.022) and last visit (p = 0.022)
* PGIC better at week 5 (p=0.037) compared to placebo arm +
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies +
No differences between arms after 5 weeks (no p-value). +
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies +
No differences between arms after 5 weeks (no p-value). +