Jump to content

Property:Results during intervention

From CAMIH
Revision as of 09:32, 25 April 2024 by Cotto (talk | contribs) (Created a property of type Text)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

This is a property of type Text.

Showing 20 pages using this property.
A
Intervention arm: mean levels of 25(OH)D increased significantly from 21 to 39 ng/mL (p=0.0001), placebo arm: no significant change (p=0.14)  +
Nausea (all three cycles): no significant difference for mean nausea in ginger vs. placebo arm Subgroup analysis for different chemotherapies: no significant arm differences  +
No statistically significant difference; median overall survival in the intervention arm was 39 months and 40 months in control arm  +
No statistically significant difference in mortality between the two groups during the 46-months follow up; median progression-free survival for both arms: 10.5 months  +
In week 2, 4 and 6 no statistically significant differences in mucositis intensity between arms; in the 8th, 12th, 16th, and 20th week of chemotherapy there were statistically significant differences between both arms (p < 0.005) No statistically significant difference in the mucositis treatment period between both arms Increased drug effect with decreased mucositis intensity over increased time in the intervention arm (p < 0.005).  +
During 2nd week no statistically significant differences in the arms; during 4th week the intensity of xerostomia in the drug arm was less than the placebo arm (p < 0.005), a trend which continued until the 16th week of treatment; during 18th week no differences; during 20th week significantly lower in the intervention arm (p < 0.005) No significant differences in terms of xerostomia treatment Increased drug effect with decreased xerostomia intensity over increased time in the intervention arm (p < 0.005).  +
From the 6th week until the 20th week less pain intensity in the intervention arm than in the placebo arm (p < 0.005) Increased drug effect with decreased degree of pain over increased time in the intervention arm (p < 0.005)  +
''Daywise comparison'' No significant arm difference at all time points: Day 1: p=0.08 Day 2: p=0.29 Day 3: p=0.17 Day 4: p= 0.16 Day 5: p=0.42 ''Mean after intervention'' No significant difference in number of retching episodes, p=0.141  +
''Daywise comparison'' At T2 (day2), T3 (day 3) and T5 (day 5) intervention arm significantly less frequent vomiting than control arm, Number of vomiting episodes mean (SD) for intervention vs. control: T2 (day 2): 0 (0.1) vs. 0.3 (0.6), p=0.01 T3 (day 3): 0 (0.1) vs. 0.2 (0.4), p=0.01 T5 (day 5): 0 (0) vs. 0.2 (0.4), p=0.04; no significant difference for T1 (day 1) or T4 (day 4) (p=0.21 and 0.07) ''Mean after intervention'' Intervention arm significantly less frequent vomiting than control arm, number of vomiting episodes mean (SD) for intervention vs. control: 0 (0) vs. 0.2 (0.3), p=0.011  +
''Daywise comparison'' At T2 (day2)-T5 (day 5) intervention arm significantly less nausea than control arm, VAS mean (SD) for intervention vs. control: T2 (day 2): 3.8 (1.9) vs. 6.3 (1.9), p<0.001 T3 (day 3): 3.8 (1.8) vs. 6.5 (1.8), p=0.001 T4 (day 4): 3.7 (1.9) vs. 6.3 (1.8), p=0.001 T5 (day 5): 2.8 (1.7) vs. 5.4 (2.3), p=0.001; no significant difference for T1 (day 1) (p=0.15) ''Mean after intervention'' Intervention arm significantly less nausea than control arm, VAS mean (SD) for intervention vs. control: 3 (1.5) vs. 5.1 (1.5), p<0.001  +