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- Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis + (Daily fraction was 180 cGy to 200 cGy in f … Daily fraction was 180 cGy to 200 cGy in five weekly fractions,</br>total dose prescribed was 7,000 cGy;</br></br>No significant difference in the radiation dose, fraction, and duration was identified between intervention and placebo arm; all patients received concomitant chemotherapy with 5-fluorouracil and cis-platinumerapy with 5-fluorouracil and cis-platinum)