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List of results

Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial + (Taxan (58%), Cisplatin (4%), Carboplatin (1%), Oxaliplatin (26%), Combination (11%))
Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy + (Taxan-based chemotherapy; paclitaxel 80 mg … Taxan-based chemotherapy; paclitaxel 80 mg/m2 once per week for 12 cycles, paclitaxel 175 mg/m2 once every 2 weeks for four cycles, paclitaxel 175 mg/m2 once every 2 weeks for six cycles, docetaxel 75 mg/m2 once every 3 weeks for four cycles, or docetaxel 75 mg/m2 once every 3 weeks for six cycles weeks for four cycles, or docetaxel 75 mg/m2 once every 3 weeks for six cycles)
Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine + (Taxan-based chemotherapy; paclitaxel 80 mg … Taxan-based chemotherapy; paclitaxel 80 mg/m2 once per week for 12 cycles, paclitaxel 175 mg/m2 once every 2 weeks for four cycles, paclitaxel 175 mg/m2 once every 2 weeks for six cycles, docetaxel 75 mg/m2 once every 3 weeks for four cycles, or docetaxel 75 mg/m2 once every 3 weeks for six cycles weeks for four cycles, or docetaxel 75 mg/m2 once every 3 weeks for six cycles)
Shamsaei et al. (2017): The Vitamin E Preventive Effect on Taxol-Induced Neuropathy Among Patients With Breast Cancer: A Randomized Clinical Trial + (Taxol-based chemotherapy)
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial + (The high-dose chemotherapy included busulf … The high-dose chemotherapy included busulfan 4 mg/kg p.o. in divided doses daily for 4 days (total dose 16 mg/kg) followed by cyclophsophamide 60 mg/kg once daily i.v. for 2 days (total dose 120 mg/kg) + peripheral blood hematopoietic stem cells 1 day after completion of chemotherapylls 1 day after completion of chemotherapy)
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study + (The location of the fungating malignant wounds were: breast (n=24), neck (n=2), groin (n=2), spine (n=1); anus (n=1))
Hajimohammadebrahim-Ketabforoush et al. (2019): Effect of Vitamin D Supplementation on Postcraniotomy Pain After Brain Tumor Surgery: A Randomized Clinical Trial + (The patients undergoing general anesthesia … The patients undergoing general anesthesia were induced with thiopental sodium 5e7 mg/kg, fentanyl 5 mg/kg, midazolam 0.02 mg/kg, lidocaine 1 mg/kg, atracurium 0.5 mg/kg, endotracheal intubation, and maintained with propofol 50e150 mg/kg/min in a 3 L/min oxygen/air mixture. Eventually, the patient’s awakening was induced with neostigmine and atropine to an extent of 0.07 mg/kg and 0.02 mg/kg, respectively.f 0.07 mg/kg and 0.02 mg/kg, respectively.)
Cruciani et al. (2009): L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study + (The protocol was amended during the course of the study, and patients receiving chemotherapy or radiation therapy were allowed under the modified protocol.)
Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial + (The radiation dose was 50-70Gy (1.8-2Gy 5x per day))

Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy + (Time since radiation therapy ''mean (range)'': 4.35 years (0.67-19))

Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer + (Treatment intent: Definitive = 86 Postoperative = 18 Induction chemotherapy: Yes = 96 No = 8)
Dörr et al. (2007): Efficacy of Wobe-Mugos E for Reduction of Oral Mucositis after Radiotherapy + (Tumors were mainly located at tonsils (20. … Tumors were mainly located at tonsils (20.5%), floor of the mouth (15.7%), or tongue (margin:15.7%, base:12.0%, body:8.4%)Patients received surgery prior to radiotherapy in n (%): both arms together: 59 (85.5%)enzyme-arm: 33 (91.7%)placebo-arm: 26 (78.8%)Radiotherapy protocols comprised conventional fractionation with 1.8–2.0 Gy/fraction, 5× per week to total doses of 60–66 Gy per 6–7 weeks, or hyperfractionation with 2 × 1.2 Gy per day, 5× per week to a total dose of 72 Gy per 6–7 weeks.ek to a total dose of 72 Gy per 6–7 weeks.)
Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer + (Types of radiotherapy per arm: - intervention: 9x radiotherapy, 16x concurrent chemoradiotherapy - placebo: 6x radiotherapy, 14x concurrent chemoradiotherapy N for adjuvant/definitive setting per arm: - intervention: 15/10 - placebo:9/11)
Beer et al. (2007): Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators + (Weekly docetaxel 36 mg/m2 intravenously and dexamethasone (4 mg orally 12 hours before, 1 hour before, and 12 hours after docetaxel administration))
Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (With no intention to cure)
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy + (With paclitaxel as first or second line treatment)
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial + (n = 11 (24%) patients received concurrent chemotherapy)
Freedland et al. (2020): A Randomized Controlled Trial of a 6-month low carbohydrate intervention on disease progression in men with recurrent prostate cancer: Carbohydrate and Prostate Study 2 (CAPS2) + (n = 45 Surgery, n (%): 36 (80) Radiation, n (%): 9 (20))